Journal article
Proceedings of the National Academy of Sciences of the United States of America, 2025
APA
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Ceceli, A., King, S., Drury, K., McClain, N., Gray, J. H., Dassanayake, P. S., … Goldstein, R. Z. (2025). The synergy of methylphenidate- and reconsolidation-based extinction normalizes ventromedial prefrontal function in drug addiction. Proceedings of the National Academy of Sciences of the United States of America.
Chicago/Turabian
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Ceceli, A., S. King, K. Drury, N. McClain, John H. Gray, P. S. Dassanayake, J. Newcorn, Daniela Schiller, N. Alia-Klein, and Rita Z. Goldstein. “The Synergy of Methylphenidate- and Reconsolidation-Based Extinction Normalizes Ventromedial Prefrontal Function in Drug Addiction.” Proceedings of the National Academy of Sciences of the United States of America (2025).
MLA
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Ceceli, A., et al. “The Synergy of Methylphenidate- and Reconsolidation-Based Extinction Normalizes Ventromedial Prefrontal Function in Drug Addiction.” Proceedings of the National Academy of Sciences of the United States of America, 2025.
BibTeX Click to copy
@article{a2025a,
title = {The synergy of methylphenidate- and reconsolidation-based extinction normalizes ventromedial prefrontal function in drug addiction},
year = {2025},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
author = {Ceceli, A. and King, S. and Drury, K. and McClain, N. and Gray, John H. and Dassanayake, P. S. and Newcorn, J. and Schiller, Daniela and Alia-Klein, N. and Goldstein, Rita Z.}
}
Significance In people with drug addiction, we report that the pharmacological enhancement of memory modulation normalized impairments in prefrontal cortex function in response to drug-associated cues, with effects associated with lab-based drug seeking the following day. These results could contribute to the development of precise therapeutic tools to dampen excessive drug-biased salience for people with addiction, as well as other relevant disorders characterized by a maladaptive response to salient memories (e.g., posttraumatic stress disorder).